A CYTOTOXIC PYRANONAPHTHOQUINONE FROM CULTURED LICHEN MYCOBIONTS OF HAEMATOMMA sp

• Published in: Heterocycles Vol. 94; no. 9; pp. 1728 - 1735
• Main Authors: Takenaka, Yukiko, Mizushina, Yoshiyuki, Hamada, Nobuo, Tanahashi, Takao
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier 2017
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; METABOLITES; GRAPHIS-SCRIPTA; DERIVATIVES; DNA; BETA

Spore-derived mycobionts of the lichen Haematomma sp. were cultivated on malt-yeast extract medium supplemented with 10% sucrose to produce a new pyranonaphthoquinone, 4, as well as two known compounds (-)-usnic acid (2) and 5-deoxy-7-methylbostrycoidin (3). The structure of 4 was determined by spec...