Preparation of Novel Electrospun Organic–Inorganic Hybrid Nanofibers Based on Polycaprolactone, Glycine Betaine, and Calcium Carbonate (P/G/CaCO3-EPnF)

Biomedicine requires materials able to respond to specific needs without affecting the organism. Organic–inorganic fibrillar polymeric matrices possess unique properties that may fulfill these needs. In the present study, different topology-controlled poly(ε-caprolactone)-based fibrillar matrices co...

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Bibliographic Details
Published inCrystals (Basel) Vol. 13; no. 4; p. 611
Main Authors Butto-Miranda, Nicole, Cabrera-Barjas, Gustavo, Ibáñez, Andrés, Neira-Carrillo, Andrónico
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.04.2023
Subjects
Analysis
Calcium carbonate
Contact angle
Crystallization
Electrospinning
Gaseous diffusion
Glycine
glycine betaine
hybrid materials
Mineralization
Nanofibers
organic–inorganic nanofibers
Polycaprolactone
Polymers
Scanning electron microscopy
Software
Spectrum analysis
Substrates
Thermodynamic properties
Thermogravimetric analysis
Topology
Chile
St Louis Missouri
United States > US
Germany
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Summary:Biomedicine requires materials able to respond to specific needs without affecting the organism. Organic–inorganic fibrillar polymeric matrices possess unique properties that may fulfill these needs. In the present study, different topology-controlled poly(ε-caprolactone)-based fibrillar matrices containing glycine betaine at varying concentrations (0.5, 1, and 2% w/v) were prepared via electrospinning. The matrices were used as substrates in calcium carbonate crystallization assays with gas diffusion to obtain a single organic–inorganic hybrid material. The resulting matrices and crystalline material were characterized using spectroscopic, microscopic, and thermogravimetric analyses. The incorporation of glycine betaine into a poly(ε-caprolactone) mesh modified the diameter of the fibers, without affecting the thermal behavior of the matrices. However, the chemical and morphological characteristics of the matrices did influence in vitro inorganic mineralization. The thermogravimetric analysis of the matrices, performed after the mineralization tests, demonstrated the existence of a new organic–inorganic hybrid material with unique properties, which is discussed in the present study.
ISSN:2073-4352
2073-4352
DOI:10.3390/cryst13040611