Isolated central nervous system metastasis from transitional cell carcinoma of the bladder: report of a case and review of the literature

• Published in: Neurosurgery Vol. 18; no. 5; p. 622
• Main Authors: Davis, R P, Spigelman, M K, Zappulla, R A, Sacher, M, Strauchen, J A
• Format: Journal Article
• Language: English
• Published: United States 01.05.1986
• Subjects: Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Aphasia - etiology; Brain Neoplasms - pathology; Brain Neoplasms - secondary; Brain Neoplasms - surgery; Carcinoma, Transitional Cell - pathology; Carcinoma, Transitional Cell - surgery; Histocytochemistry; Humans; Male; Middle Aged; Neoplasm Recurrence, Local - drug therapy; Postoperative Complications; Tomography, X-Ray Computed; Urinary Bladder Neoplasms - pathology; Urinary Bladder Neoplasms - surgery
• ISSN: 0148-396X
• DOI: 10.1227/00006123-198605000-00018

Although systemic metastases from transitional cell carcinoma of the bladder occur frequently, involvement of the central nervous system is uncommon. We describe a patient with an isolated cerebral metastasis who had previously undergone resection of a Grade III, Stage B2 carcinoma of the bladder. We have been able to find only one previous case report of a solitary intracerebral metastasis from transitional cell carcinoma of the bladder without evidence of primary recurrence or additional sites of spread. Central nervous system metastasis from bladder carcinoma must be considered in the differential diagnosis of solitary intracerebral lesions.