Miliary Nodules: Not Always Tuberculosis

Mutations in the epidermal growth factor receptor (EGFR) gene and rearrangements of the ALK gene are two of the most common driver mutations in lung adenocarcinoma. According to this patient's risk factors, the most likely diagnostic considerations are miliary tuberculosis, fungal infection (e....

Full description

Saved in:
Bibliographic Details
Published inAnnals of the American Thoracic Society Vol. 14; no. 12; pp. 1858 - 1860
Main Authors Kimmig, Lucas, Bueno, Juliana
Format Journal Article
LanguageEnglish
Published United States American Thoracic Society 01.12.2017
Subjects
Adenocarcinoma of Lung - diagnosis
Adenocarcinoma of Lung - secondary
Biopsy
Bronchoscopy
Diagnosis, Differential
Fungal infections
Humans
Laboratories
Lumbar Vertebrae
Lung - diagnostic imaging
Lung cancer
Lung diseases
Male
Medical imaging
Metastasis
Middle Aged
Mutation
Neoplasm Metastasis
Nervous system
Patients
Radiography, Thoracic
Spinal Neoplasms - diagnosis
Spinal Neoplasms - secondary
Tomography, X-Ray Computed - methods
Tuberculosis
Tuberculosis, Miliary - diagnosis
United States > US
China
Online AccessGet full text

Cover

More Information
Summary:Mutations in the epidermal growth factor receptor (EGFR) gene and rearrangements of the ALK gene are two of the most common driver mutations in lung adenocarcinoma. According to this patient's risk factors, the most likely diagnostic considerations are miliary tuberculosis, fungal infection (e.g., histoplasmosis or blastomycosis given our midwestern location), and metastatic disease. The mass in the lumbar spine that caused the initial symptoms was confirmed to represent a distant metastasis of a primary lung cancer.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:2329-6933
2325-6621
DOI:10.1513/AnnalsATS.201706-436CC