Epidermotropic metastases from internal carcinomas

Four cases of epidermotropically metastatic carcinoma are reported. One of them originated from a breast adenocarcinoma; in two other cases, the primary tumor was located in the large intestine; and, in the fourth case, the primary malignancy was a laryngeal squamous cell carcinoma. Clinically, the...

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Bibliographic Details
Published inThe American journal of dermatopathology Vol. 13; no. 5; p. 452
Main Authors Aguilar, A, Schoendorff, C, Lopez Redondo, M J, Ambrojo, P, Requena, L, Sanchez Yus, E
Format Journal Article
LanguageEnglish
Published United States 01.10.1991
Subjects
Aged
Breast Neoplasms - pathology
Female
Humans
Intestinal Neoplasms - pathology
Laryngeal Neoplasms - pathology
Male
Middle Aged
Skin Neoplasms - pathology
Skin Neoplasms - secondary
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Summary:Four cases of epidermotropically metastatic carcinoma are reported. One of them originated from a breast adenocarcinoma; in two other cases, the primary tumor was located in the large intestine; and, in the fourth case, the primary malignancy was a laryngeal squamous cell carcinoma. Clinically, the cutaneous metastases were nodular lesions and histologically, in addition to the involvement of the dermis by malignant cells, in three cases there was intraepidermal involvement by glandular structures. In the fourth case, the cutaneous metastatic tumor cells showed striking "folliculotropism." We review the literature of epidermotropically metastatic carcinoma and discuss its differential diagnosis.
ISSN:0193-1091
DOI:10.1097/00000372-199110000-00004