Evaluation of Thyroid Scintigraphy in Small Animals

Thyroid scintigraphy in rats and mice with 99mTC and 123I was attempted to examine whether this modality might be used in small animals and to describe the possibilities of its application in examing experimentally produced thyroid diseases. A human gamma camera with a pinhole collimator improved fo...

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Published inRADIOISOTOPES Vol. 38; no. 8; pp. 344 - 346
Main Authors KANEKO, Masayuki, KOBAYASHI, Terumichi, TAKANO, Hideaki, OHNISHI, Takashi, KAKU, Touei, NISHI, Tomoko, KAWASE, Chikage, KANEKO, Kazuko
Format Journal Article
LanguageJapanese
English
Published Japan Japan Radioisotope Association 01.08.1989
Subjects
Animals
Animals, Laboratory - diagnostic imaging
Disease Models, Animal
experimentally produced thyroid disease
Iodine Radioisotopes
iodine-123
Mice
pinhole collimator
Radionuclide Imaging
Rats
Technetium
technetium-99m
Thyroid Diseases - diagnostic imaging
Thyroid Gland - diagnostic imaging
thyroid scintigraphy
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Summary:Thyroid scintigraphy in rats and mice with 99mTC and 123I was attempted to examine whether this modality might be used in small animals and to describe the possibilities of its application in examing experimentally produced thyroid diseases. A human gamma camera with a pinhole collimator improved for small animals was used for imaging. Thyroid images with 99mTc were obtained 20 minutes after injection and those with 123I were 24 hours after administration. All the scintigrams, although those obtained from mice with 99mTc displayed overlapped salivary gland images, demonstrated sufficiently clear images in size and shape, which showed that thyroid scintigraphy in small animals should be applicable in examining experimentally produced thyroid disases.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0033-8303
1884-4111
DOI:10.3769/radioisotopes.38.8_344