The potential of salivary albumin to degrade composite resin

Albumin is a salivary enzyme capable of cleaving ester linkages and catalyzing degradation of resin-based dental materials. However, the effect of concentration-dependent esterolytic action on composite resins as yet remains unexplored. The purpose of this study was to evaluate whether artificial sa...

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Published inActa odontológica latinoamericana Vol. 36; no. 1; pp. 34 - 39
Main Authors Barros, Leonardo S, Denucci, Giovanna C, Amoral, Flávia Lb, Franga, Fabiana Mg, Basting, Roberta T, Turssi, Cecilia P
Format Journal Article
LanguageEnglish
Published Argentina Sociedad Argentina de Investigación Odontológica 29.04.2023
Subjects
Albumins
Composite Resins
DENTISTRY, ORAL SURGERY & MEDICINE
Esters
Original
Saliva, Artificial
saliva
composite resins
aging
hydrolysis
albumin
hidrólise
envelhecimento
resinas compostas
albumina
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Summary:Albumin is a salivary enzyme capable of cleaving ester linkages and catalyzing degradation of resin-based dental materials. However, the effect of concentration-dependent esterolytic action on composite resins as yet remains unexplored. The purpose of this study was to evaluate whether artificial saliva formulations with different concentrations of albumin affected the surface roughness, flexural strength and microhardness of a composite resin. Specimens (25x2x2mm) of a nanofilled composite (Filtek Z350XT, 3M/ESPE) were prepared and analyzed for average surface roughness (Ra/pm). The specimens were then allocated to 6 groups (n=30), to be treated with different salivary albumin concentrations: 0, 10, 50, 100, 200, 400 pg/mL. The specimens were stored in their respective artificial saliva groups, half of them for 24 h and the remainder for 180 days (artificial saliva renewed weekly), after which they were submitted to a new Ra reading, and tested for three-point flexural strength (FS, MPa). The specimens stored for 180 days were analyzed for Knoop microhardness (KH, Kg/mm ). Data were submitted to two-way ANOVA (Ra and FS) and one-way ANOVA (KH). Although Ra increased (p < 0.001) and FS decreased (p < 0.001) from 24 hours to 180 days of storage, the albumin concentration did not significantly affectRa (p = 0.168), FS (p = 0.477) or KH (p = 0.378). The esterolytic action of albumin did not increase the artificial-saliva-induced hydrolytic degradation of the composite resin.
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DECLARATION OF CONFLICTING INTERESTS The authors declare no potential conflicts of interest regarding the research, authorship, and/or publication of this article.
ISSN:1852-4834
0326-4815
1852-4834
DOI:10.54589/aol.36/1/34