Hyaluronan and phospholipids in boundary lubrication

Hyaluronan has been found to play an important role in boundary lubrication in joints, but model experiments have shown that free hyaluronan is reluctant to stay between surfaces. We show that hyaluronan, when assisted by a phospholipid bilayer, can act as a boundary lubricant, even at pressures wel...

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Bibliographic Details
Published inSoft matter Vol. 8; no. 40; pp. 10241 - 10244
Main Authors Liu, Chao, Wang, Min, An, Junxue, Thormann, Esben, Dėdinaitė, Andra
Format Journal Article
LanguageEnglish
Published 01.01.2012
Subjects
Boundary lubricants
Boundary lubrication
Boundary lubrications
Breakdown
Cartilage
Chemistry
Hyaluronan
Hyaluronan and phospholipids in boundary lubrication
Lubricants
Lubrication
Materials science
Model experiments
Phospholipid bilayer
Phospholipids
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Summary:Hyaluronan has been found to play an important role in boundary lubrication in joints, but model experiments have shown that free hyaluronan is reluctant to stay between surfaces. We show that hyaluronan, when assisted by a phospholipid bilayer, can act as a boundary lubricant, even at pressures well above those leading to breakdown of cartilage.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1744-683X
1744-6848
1744-6848
DOI:10.1039/c2sm26615f