Reticular framework materials in miniaturized and emerging formats in analytical chemistry

• Published in: Journal of Chromatography A Vol. 1673; p. 463092
• Main Authors: Martínez-Pérez-Cejuela, Héctor, Carrasco-Correa, Enrique Javier, Moga, Ancuta, Vergara-Barberán, María, Beneito-Cambra, Miriam, Lerma-García, María Jesús, Simó-Alfonso, Ernesto Francisco, Herrero-Martínez, José Manuel
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 21.06.2022
• Subjects: (Bio)sensing; Analytical applications; Covalent-organic frameworks; Metal-organic frameworks; Off-site analysis; Smart devices; Analytical applications; Covalent-organic frameworks; Off-site analysis; Metal-organic frameworks; Smart devices; (Bio)sensing
• ISSN: 0021-9673; 1873-3778
• DOI: 10.1016/j.chroma.2022.463092

•State-of-the-art of MOF/COF-based materials with miniaturized analytical formats is reviewed.•Synthesis, properties and structures of MOFs/COFs is summarized.•Benefits and limitations of chips, 3D-printed objects and PADs are discussed.•The preparation of MOF/COFs in these analytical platforms is debated.•Challenges and future perspectives on reticular materials in these formats are indicated. In recent years, important efforts have been put into miniaturization, coming on the scene formats such as chips, 3D-printed objects and paper-based devices. These systems have been applied to biological and chemical processes taking profit of their advantages such as waste reduction, low cost, portability, etc. Despite their benefits, there is a need to continue developing easier-to-use devices with enhanced performance addressed to face the current analytical challenges. In this sense, reticular porous materials such as metal- (MOFs) and covalent- (COFs) organic frameworks with unique features including tailorable porous architectures and tunable chemistry have attracted a lot of attention in various fields. Nevertheless, the combination of these materials with miniaturized and emerging formats has been scarcely investigated. This review is intended to bridge this gap and highlight the recent contributions of these materials in these analytical formats. Thus, this work aims to provide a comprehensive review of the field, highlighting incorporation strategies into the functional supports available to date, and the applications of the resulting systems in both off-site laboratory studies (mostly dedicated to (micro)extraction purposes) and on-site analysis. Finally, a discussion of challenges and future directions in this field is also given.