Comment on "Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals"

Pinson . ( ) concluded that the modern human gene is responsible for an increased number of cortical neurons. We show that the "putative Neanderthal variant" of is present in modern human backgrounds. We dispute their argument that this genetic variant is responsible for brain differences...

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Published inScience (American Association for the Advancement of Science) Vol. 379; no. 6636; p. eadf0602
Main Authors Herai, Roberto H, Semendeferi, Katerina, Muotri, Alysson R
Format Journal Article
LanguageEnglish
Published United States 10.03.2023
Subjects
Animals
Humans
Neanderthals - genetics
Neocortex - growth & development
Neurogenesis - genetics
Transketolase
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Summary:Pinson . ( ) concluded that the modern human gene is responsible for an increased number of cortical neurons. We show that the "putative Neanderthal variant" of is present in modern human backgrounds. We dispute their argument that this genetic variant is responsible for brain differences in modern humans as opposed to Neanderthals.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0036-8075
1095-9203
DOI:10.1126/science.adf0602