One-pot synthesis, characterization, photocatalytic activity and biological studies of Co(II), Ni(II) and Cu(II) complexes of a tetraazamacrocyclic Schiff base

• Published in: Journal of coordination chemistry Vol. 76; no. 5-6; pp. 729 - 748
• Main Authors: Remiya, J. P., Shyni, B., Sikha, T. S., Parvathy, U. R.
• Format: Journal Article
• Language: English
• Published: Abingdon Taylor & Francis 19.03.2023; Taylor & Francis Ltd
• Subjects: Absorption spectra; Base metal; Biocompatibility; Biological activity; biological applications; Catalytic activity; Chemical analysis; Coordination compounds; Copper; Free radicals; Imines; Magnetic moments; Magnetic permeability; Nickel; NMR; Nuclear magnetic resonance; one-pot synthesis; Photocatalysis; photocatalytic efficiency; Scavenging; Schiff base macrocycles; template condensation; Thermal decomposition; Toxicity; Water splitting
• ISSN: 0095-8972; 1029-0389
• DOI: 10.1080/00958972.2023.2199440

Template condensation between pentane-1,5-dial and triethylenetetramine in the presence of divalent metal salts in methanolic solution resulted in mononuclear 15-membered tetraazamacrocyclic Schiff base metal complexes, [M(C 11 H 22 N 4 )X 2 ], where M = Co(II), Ni(II) and Cu(II), X = Cl − and C 11 H 22 N 4 is the tetradentate macrocyclic ligand. The bonding and overall geometry of the complexes are inferred through elemental analysis, FT-IR, UV-vis, 1 H/ 13 C NMR, ESI-mass, molar conductance, magnetic susceptibility and TG measurements. On the basis of the absorption bands in UV-vis spectra and magnetic moment analyses, a six-coordinate octahedral geometry is proposed for all the metal complexes. The formulation of the metal chelates is compatible with the thermal decomposition profiles. Photocatalytic efficiency of the macrocyclic Ni(II) complex was studied using solar water-splitting. The in vitro antimicrobial activity of metal complexes has been tested against certain bacterial and fungal species. The scavenging ability of DPPH free radicals was used to test the antioxidant activity of the complexes. In addition, MTT assay was used to assess the cytotoxicity of Cu(II) chloro complex against L929 mouse fibroblast cell lines.