Metal-organic frameworks/polydopamine coating endows polyetheretherketone with disinfection and osteogenicity

The work describes a polydopamine-wrapped zeolitic imidazolate framework-8 (ZIF-8) coating constructed on the sulfonated polyetheretherketone (PEEK). The coating is not only conducive to the controllable Zn 2+ releases, but also exhibits excellent photothermal capacity under near-infrared (NIR) irra...

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Published inInternational journal of polymeric materials Vol. 71; no. 10; pp. 783 - 794
Main Authors Chen, Yong, Yang, Qizhang, Ma, Daichuan, Peng, Liming, Mao, Yurong, Zhou, Xiong, Deng, Yi, Yang, Weizhong
Format Journal Article
LanguageEnglish
Published Philadelphia Taylor & Francis 03.07.2022
Taylor & Francis Ltd
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Summary:The work describes a polydopamine-wrapped zeolitic imidazolate framework-8 (ZIF-8) coating constructed on the sulfonated polyetheretherketone (PEEK). The coating is not only conducive to the controllable Zn 2+ releases, but also exhibits excellent photothermal capacity under near-infrared (NIR) irradiation. in vitro antibacterial experiments indicate the coating possesses bactericidal efficiencies of 100% against Staphylococcus aureus and Escherichia coli under NIR. Without NIR, the ZIF-8/pDA-functionalized substrate shows favorable biocompatibility and enhanced osteogenic activities. We are convinced that this study may provide prospective opinions for developing the PEEK implants with photoinduced disinfection and osteogenesis for the repair of infected bone defects.
ISSN:0091-4037
1563-535X
DOI:10.1080/00914037.2021.1909585