E-Test: An Alternative Method for Susceptibility Testing of Mycobacterium tuberculosis

Objective: The purpose of this study was to compare the agar proportion method with the E-test method for susceptibility testing of Mycobacterium tuberculosis.Materials and Methods: A total of 100 isolates were tested for isoniazid, rifampin, streptomycin and ethambutol susceptibility using an indir...

Full description

Saved in:
Bibliographic Details
Published inMedical principles and practice Vol. 14; no. 4; pp. 264 - 267
Main Authors Akcali, Sinem, Cicek, Candan, Surucuoglu, Suheyla, Ozbakkaloglu, Beril
Format Journal Article
LanguageEnglish
Published Basel, Switzerland 01.07.2005
Subjects
Agar
Antibiotics, Antitubercular - pharmacology
Colony Count, Microbial
Drug Resistance, Bacterial
Ethambutol - pharmacology
In Vitro Techniques
Isoniazid - pharmacology
Microbial Sensitivity Tests - methods
Mycobacterium tuberculosis - drug effects
Original Paper
Rifampin - pharmacology
Sensitivity and Specificity
Streptomycin - pharmacology
Tuberculosis
Agar proportion
E-test
Susceptibility
Online AccessGet full text

Cover

More Information
Summary:Objective: The purpose of this study was to compare the agar proportion method with the E-test method for susceptibility testing of Mycobacterium tuberculosis.Materials and Methods: A total of 100 isolates were tested for isoniazid, rifampin, streptomycin and ethambutol susceptibility using an indirect-proportion method as well as the E-test method. Results:Categorical agreement between the methods was 100% for isoniazid, rifampin, streptomycin, and ethambutol. Conclusion: The E-test method appears to be an alternative method to agar proportion for testing the susceptibility of M. tuberculosis isolates to the first-line antituberculous agents.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1011-7571
1423-0151
DOI:10.1159/000085747