Recent trends toward the synthesis of fused-benzothiazines and their derivatives

Fused-benzothiazines are of much interest for various fields of science as these scaffolds demonstrate a wide spectrum of biological applications like anti-microbial, anti-malarial, anti-cancer, anti-viral, ant-oxidant, anti-inflammatory, etc. These heterocycles are often constructed via formation o...

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Bibliographic Details
Published inSynthetic communications Vol. 51; no. 3; pp. 351 - 378
Main Authors Ahmad Saddique, Furqan, Ahmad, Matloob, Kanwal, Afshan, Aslam, Sana, Fawad Zahoor, Ameer
Format Journal Article
LanguageEnglish
Published Philadelphia Taylor & Francis 01.02.2021
Taylor & Francis Ltd
Subjects
2-Aminothiophenol
Antiinfectives and antibacterials
Catalysts
fused-benzothiazines
Iodine
isothiocyanate
Microorganisms
Oxidizing agents
sulfonamides
Synthesis
Transition metals
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Summary:Fused-benzothiazines are of much interest for various fields of science as these scaffolds demonstrate a wide spectrum of biological applications like anti-microbial, anti-malarial, anti-cancer, anti-viral, ant-oxidant, anti-inflammatory, etc. These heterocycles are often constructed via formation of C-N/C-S bonds in the presence of catalysts such as transition metals, molecular iodine, etc. or under catalyst-free conditions. In this review, we have focused different methodologies for the synthesis of fused-benzothiazines reported during 2015-2019.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397911.2020.1830420