Naringenin as a Natural Agent Against Oxidative Stress and Inflammation, and Its Bioavailability
Naringenin is a flavanone commonly found in citrus and aromatic herbs that can protect against oxidative stress and inflammation. Oxidative stress can cause serious damage to tissues and organs; furthermore, it is closely related to chronic inflammation-related diseases, as reactive oxygen species c...
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Published in | Food reviews international Vol. 39; no. 9; pp. 6707 - 6745 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Philadelphia
Taylor & Francis
03.10.2023
Taylor & Francis Ltd |
Subjects | |
Online Access | Get full text |
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Abstract | Naringenin is a flavanone commonly found in citrus and aromatic herbs that can protect against oxidative stress and inflammation. Oxidative stress can cause serious damage to tissues and organs; furthermore, it is closely related to chronic inflammation-related diseases, as reactive oxygen species can activate transcription factors that culminate in the production of pro-inflammatory molecules. The effects of naringenin against these responses are mediated by its antioxidant capacity and the induction or inhibition of signaling routes related to inflammation. Hence the current review summarizes the current knowledge of naringenin's health benefits against oxidative stress and inflammation, its mechanisms of action, and its bioavailability. |
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AbstractList | Naringenin is a flavanone commonly found in citrus and aromatic herbs that can protect against oxidative stress and inflammation. Oxidative stress can cause serious damage to tissues and organs; furthermore, it is closely related to chronic inflammation-related diseases, as reactive oxygen species can activate transcription factors that culminate in the production of pro-inflammatory molecules. The effects of naringenin against these responses are mediated by its antioxidant capacity and the induction or inhibition of signaling routes related to inflammation. Hence the current review summarizes the current knowledge of naringenin's health benefits against oxidative stress and inflammation, its mechanisms of action, and its bioavailability. |
Author | Elizalde-Romero, Cristina Alicia Gutiérrez-Grijalva, Erick P. Heredia, J. Basilio Leyva-López, Nayely Picos-Salas, Manuel Adrian Cabanillas-Bojórquez, Luis Ángel Montoya-Inzunza, Luis Aurelio |
Author_xml | – sequence: 1 givenname: Manuel Adrian orcidid: 0000-0001-8899-1029 surname: Picos-Salas fullname: Picos-Salas, Manuel Adrian organization: Centro de Investigación en Alimentación y Desarrollo A.C – sequence: 2 givenname: Luis Ángel orcidid: 0000-0002-8943-2891 surname: Cabanillas-Bojórquez fullname: Cabanillas-Bojórquez, Luis Ángel organization: Centro de Investigación en Alimentación y Desarrollo A.C – sequence: 3 givenname: Cristina Alicia orcidid: 0000-0002-2338-9894 surname: Elizalde-Romero fullname: Elizalde-Romero, Cristina Alicia organization: Centro de Investigación en Alimentación y Desarrollo A.C – sequence: 4 givenname: Nayely orcidid: 0000-0001-6222-6169 surname: Leyva-López fullname: Leyva-López, Nayely organization: Centro de Investigación en Alimentación y Desarrollo A.C – sequence: 5 givenname: Luis Aurelio orcidid: 0000-0003-3327-1053 surname: Montoya-Inzunza fullname: Montoya-Inzunza, Luis Aurelio organization: Centro de Investigación en Alimentación y Desarrollo A.C – sequence: 6 givenname: J. Basilio orcidid: 0000-0003-1017-957X surname: Heredia fullname: Heredia, J. Basilio organization: Centro de Investigación en Alimentación y Desarrollo A.C – sequence: 7 givenname: Erick P. orcidid: 0000-0002-1366-408X surname: Gutiérrez-Grijalva fullname: Gutiérrez-Grijalva, Erick P. email: erickpaulggrijalva@gmail.com organization: Cátedras CONACYT-Centro de Investigación en Alimentación y Desarrollo A.C |
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SubjectTerms | Bioavailability extraction Inflammation MAPK Naringenin NF-κB Nrf2, cytokines Oxidative stress Reactive oxygen species Transcription factors |
Title | Naringenin as a Natural Agent Against Oxidative Stress and Inflammation, and Its Bioavailability |
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