Naringenin as a Natural Agent Against Oxidative Stress and Inflammation, and Its Bioavailability

Naringenin is a flavanone commonly found in citrus and aromatic herbs that can protect against oxidative stress and inflammation. Oxidative stress can cause serious damage to tissues and organs; furthermore, it is closely related to chronic inflammation-related diseases, as reactive oxygen species c...

Full description

Saved in:
Bibliographic Details
Published inFood reviews international Vol. 39; no. 9; pp. 6707 - 6745
Main Authors Picos-Salas, Manuel Adrian, Cabanillas-Bojórquez, Luis Ángel, Elizalde-Romero, Cristina Alicia, Leyva-López, Nayely, Montoya-Inzunza, Luis Aurelio, Heredia, J. Basilio, Gutiérrez-Grijalva, Erick P.
Format Journal Article
LanguageEnglish
Published Philadelphia Taylor & Francis 03.10.2023
Taylor & Francis Ltd
Subjects
Bioavailability
extraction
Inflammation
MAPK
Naringenin
NF-κB
Nrf2, cytokines
Oxidative stress
Reactive oxygen species
Transcription factors
Online AccessGet full text

Cover

More Information
Summary:Naringenin is a flavanone commonly found in citrus and aromatic herbs that can protect against oxidative stress and inflammation. Oxidative stress can cause serious damage to tissues and organs; furthermore, it is closely related to chronic inflammation-related diseases, as reactive oxygen species can activate transcription factors that culminate in the production of pro-inflammatory molecules. The effects of naringenin against these responses are mediated by its antioxidant capacity and the induction or inhibition of signaling routes related to inflammation. Hence the current review summarizes the current knowledge of naringenin's health benefits against oxidative stress and inflammation, its mechanisms of action, and its bioavailability.
ISSN:8755-9129
1525-6103
DOI:10.1080/87559129.2022.2123502