RENIN-SECRETING OVARIAN ADULT GRANULOSA CELL TUMOR IN A PATIENT WITH NEW-ONSET HYPERTENSION AND HYPOKALEMIA

To describe a case of a renin-secreting ovarian tumor, which is a rare cause of hyperreninemia leading to secondary hypertension and hypokalemia. We present the first case of a patient with a molecularly confirmed renin-secreting ovarian adult granulosa cell tumor. A 31-year-old female presented wit...

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Published inAACE clinical case reports Vol. 5; no. 2; pp. e168 - e171
Main Authors Karaman, Rowan, Xu, Jin, Harrison, Ross F, Kushner, David M, Weisman, Paul S, Shenker, Yoram
Format Journal Article
LanguageEnglish
Published United States American Association of Clinical Endocrinologists 01.03.2019
Elsevier
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Case Reports
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Summary:To describe a case of a renin-secreting ovarian tumor, which is a rare cause of hyperreninemia leading to secondary hypertension and hypokalemia. We present the first case of a patient with a molecularly confirmed renin-secreting ovarian adult granulosa cell tumor. A 31-year-old female presented with hypertension and amenorrhea. She was found to have spontaneous hypokalemia. Computed tomography scan showed a pelvic mass which was resected and found to be a renin-secreting ovarian adult granulosa cell tumor. The hypertension and hypokalemia resolved after the mass was resected. Renin-secreting ovarian adult granulosa cell tumors are rare causes of hyperreninemia leading to hypertension and hypokalemia.
Bibliography:From the Departments of 1Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
3Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
2Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
ISSN:2376-0605
2376-0605
DOI:10.4158/ACCR-2018-0355