Occurrence and Timing of Subsequent Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-transcription Polymerase Chain Reaction Positivity Among Initially Negative Patients

Abstract Using data for 20 912 patients from 2 large academic health systems, we analyzed the frequency of severe acute respiratory syndrome coronavirus 2 reverse-transcription polymerase chain reaction test discordance among individuals initially testing negative by nasopharyngeal swab who were ret...

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Published inClinical infectious diseases Vol. 72; no. 2; pp. 323 - 326
Main Authors Long, Dustin R, Gombar, Saurabh, Hogan, Catherine A, Greninger, Alexander L, O’Reilly-Shah, Vikas, Bryson-Cahn, Chloe, Stevens, Bryan, Rustagi, Arjun, Jerome, Keith R, Kong, Christina S, Zehnder, James, Shah, Nigam H, Weiss, Noel S, Pinsky, Benjamin A, Sunshine, Jacob E
Format Journal Article
LanguageEnglish
Published US Oxford University Press 27.01.2021
Subjects
COVID-19
COVID-19 Testing
Humans
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
SARS-CoV-2
COVID-19
SARS-CoV-2
RT-PCR
nasopharyngeal
test characteristics
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Summary:Abstract Using data for 20 912 patients from 2 large academic health systems, we analyzed the frequency of severe acute respiratory syndrome coronavirus 2 reverse-transcription polymerase chain reaction test discordance among individuals initially testing negative by nasopharyngeal swab who were retested on clinical grounds within 7 days. The frequency of subsequent positivity within this window was 3.5% and was similar across institutions.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1058-4838
1537-6591
1537-6591
DOI:10.1093/cid/ciaa722