Role of Sclerostin in the Bone Loss of Postmenopausal Chinese Women with Type 2 Diabetes

• Published in: Chinese medical sciences journal Vol. 28; no. 3; pp. 135 - 139
• Main Authors: Zhou, Yi-jun, Li, Ai, Song, Yu-ling, Zhou, Hui, Li, Yan, Tang, Yin-si
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.09.2013; Department of Endocrinology and Metabolism, Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China
• Subjects: 2型糖尿病; Aged; Alkaline Phosphatase - blood; Asian Continental Ancestry Group; Biomarkers - blood; bone markers; bone mineral density; Bone Morphogenetic Proteins - blood; China - epidemiology; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - epidemiology; Female; Genetic Markers; Hemoglobin A - metabolism; Humans; Middle Aged; Osteocytes - metabolism; Osteocytes - pathology; Osteoporosis, Postmenopausal - blood; Osteoporosis, Postmenopausal - epidemiology; Parathyroid Hormone - blood; postmenopause; Retrospective Studies; sclerostin; type 2 diabetes mellitus; 中国; 妇女; 硬化; 绝经后; 蛋白; 质量指数; 骨质; China; type 2 diabetes mellitus; bone mineral density; bone markers; postmenopause; sclerostin
• ISSN: 1001-9294
• DOI: 10.1016/S1001-9294(13)60038-3

Objective To evaluate the role of sclerostin in bone loss of postmenopausal Chinese women with type 2 diabetes me｜litus. Methods The postmenopausal patients suffering from type 2 diabetes mellitus and age, body mass index, and duration of menopause matched healthy controls were enrolled into this cross-sectional study according to criteria of inclusion and exclusion.