Wearable biomolecule smart sensor based on Au@PB NPs with high electrochemical activity

• Published in: Journal of alloys and compounds Vol. 891; p. 161983
• Main Authors: Zhang, Wenrui, Ma, Junlin, Meng, Fanxing, Jiang, Yu, Shen, Liuxue, Sun, Tongrui, Qin, Yanan, Zhu, Nan, Zhang, Minwei
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 25.01.2022; Elsevier BV
• Subjects: Au@PB NPs; Biomarkers; Biomolecules; Biosensors; Core-shell structure; Enzyme sensor; Flexible components; Glucose biosensor; Microfluidics; Nanomaterials; Pigments; Screen printing; Sensitivity; Sensors; Smart sensors; Substrates; Wearable biomolecule sensor; Wearable technology; Enzyme sensor; Au@PB NPs; Glucose biosensor; Wearable biomolecule sensor
• ISSN: 0925-8388; 1873-4669
• DOI: 10.1016/j.jallcom.2021.161983

•Core-shell structural Au@PB NPs were prepared, which shown highly electrochemical activity with rate constants (Кs) 600 S−1.•One-step synthesis of low-cost, high-performance mixed ink as sensor working electrode.•Au@PB NPs-based flexible biosensor exhibits excellent performance for detection of biomarkers, such as H2O2 and glucose.•As-prepared enzyme glove sensor displayed promising potential for fabrication of wearable sensor for glucose monitoring. Wearable biosensors have aroused great interest because of their potential to provide continuous and real-time physiological information through dynamic and fast response to biochemical markers in biological fluids. When the wearable sensor is used for fluid detection, required to sensors own high sensitivity and low detection limit since the complex substrate and trace amount of target. Therefore, prepared high response nanomaterials play a crucial for fabrication of wearable sensors. In our work, Prussian blue nanomaterials with core-shell structure was successfully synthesized via using Au NPs as catalyst, as prepared core-shell structural Au@PB NPs exhibited high electrochemical activity, wonderful water solubility and high stability. Then combined with screen printing technology to construct highly stable flexible sensors for the detection of biomarkers with sensitivities 301.5 μA·mM−1·cm−2 and 29.3 μA·mM−1·cm−2 respectively. Furthermore, combined with microfluidic technology, it is expected to be used in health management monitoring and clinical application on a large scale.