Efficacy of dietary and injected vitamin E for poults

• Published in: Poultry science Vol. 75; no. 11; pp. 1393 - 1403
• Main Authors: Soto-Salanova, M.F. (Iowa State University, Ames, IA.), Sell, J.L
• Format: Journal Article
• Language: English
• Published: England 01.11.1996
• Subjects: ACTIVIDAD ENZIMATICA; ACTIVITE ENZYMATIQUE; Administration, Oral; AGE; AGE DIFFERENCES; ANIMALES JOVENES; Animals; BLOOD PLASMA; Body Weight - physiology; COU; CREATINA QUINASA; CREATINE KINASE; Creatine Kinase - physiology; DIET; Diet - standards; Diet - veterinary; DIETA; DINDON; DOSAGE; Dose-Response Relationship, Drug; EDAD; EFFICACITE ALIMENTAIRE; EFICIENCIA DE CONVERSION DEL PIENSO; ENZYMIC ACTIVITY; ERITROCITOS; ERYTHROCYTE; ERYTHROCYTE FRAGILITY; ERYTHROCYTES; Erythrocytes - chemistry; FEED CONVERSION EFFICIENCY; FOIE; Glycine max - standards; HIGADO; INJECTION; Injections, Subcutaneous - veterinary; INYECCION; JEUNE ANIMAL; LIPID PEROXIDATION; LIVER; MAIS; MAIZ; MAIZE; Male; NECK; PAVO; PEROXIDACION LIPIDICA; PEROXYDATION DES LIPIDES; PESCUEZO; PESO; PLASMA SANGUIN; PLASMA SANGUINEO; POIDS; Random Allocation; REGIME ALIMENTAIRE; SOYBEAN MEAL; SOYBEAN OILMEAL; SUBCUTANEOUS INJECTION; Time Factors; TOCOFEROLES; TOCOPHEROL; TOCOPHEROLS; TORTAS DE SOJA; TOURTEAU DE SOJA; TRIGLICERIDOS; TRIGLYCERIDE; TRIGLYCERIDES; Triglycerides - blood; TURKEYS; Turkeys - blood; Turkeys - physiology; Vitamin E - administration & dosage; Vitamin E - analysis; Vitamin E - pharmacology; VITAMIN E ACETATE; WEIGHT; YOUNG ANIMALS; Zea mays - standards
• ISSN: 0032-5791; 1525-3171
• DOI: 10.3382/ps.0751393

An experiment was conducted to compare the efficacy of two dietary sources and an injectable form of vitamin E (VE) to improve the VE status of poults. Six of the treatments consisted of a factorial arrangement of three concentrations and two sources of dietary VE. Turkeys in these treatments received 12, 80, or 150 IU of either dl-alpha-tocopheryl acetate or d-alpha-tocopherol (d-alpha-TOC)/kg of diet. The seventh treatment consisted of a single subcutaneous injection of d-alpha-TOC at 1 d of age. Poults in this treatment were subcutaneously injected in the dorsal area of the neck with 25 IU of d-alpha-TOC, this amount being approximately equivalent to the amount poults would consume if their diet was supplemented with 150 IU of VE/kg during their 1st wk of life. Concentration, source, or route of VE administration did not affect growth parameters, plasma creatine kinase, plasma triglycerides, or liver lipid peroxidation as measured by the thiobarbituric acid reactive substances assay (TBARS). Plasma, red blood cells (RBC), and liver alpha-TOC decreased from hatching to 14 d of age in poults fed either source of VE. The use of 80 or 150 IU of dietary VE (either source) reduced (P < 0.05) the extent of depletion of alpha-TOC at all ages and also reduced the susceptibility of RBC to hemolysis. There was no effect of source of dietary VE on concentration of alpha-TOC in plasma, RBC, or liver, or on RBC hemolysis. Subcutaneous injection of 25 IU of d-alpha-TOC at Day 1 increased (P < 0.05) alpha-TOC concentration until 7 d of age. Also, d-alpha-TOC injection reduced (P < 0.05) RBC susceptibility to hemolysis through 21 d of age. Data showed that one single subcutaneous injection of 25 IU of d-alpha-TOC at 1 d of age was as effective as 80 IU or more of dietary VE through 21 d to improve the alpha-TOC status of poults.