Controlled ovarian hyperstimulation: an adjunct to assisted reproductive technology

• Published in: Fertility and sterility Vol. 61; no. 6; pp. 1158 - 1160
• Main Authors: Mascarenhas, Lawrence, Khastgir, Gautam, Davies, W.A.R., Lee, Sammy
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.06.1994; Elsevier Science
• Subjects: Adult; Biological and medical sciences; Birth control; Female; Gynecology. Andrology. Obstetrics; Humans; Infertility, Female - epidemiology; Infertility, Female - therapy; Medical sciences; Ovarian hyperstimulation; Ovarian Hyperstimulation Syndrome - epidemiology; Ovarian Hyperstimulation Syndrome - physiopathology; Ovulation Induction; Prospective Studies; Reproduction - physiology; Sterility. Assisted procreation; Ovarian hyperstimulation; ART; Human; Stimulation; Conjugal sterility; Therapeutic protocol; Induction; Ovulation
• ISSN: 0015-0282; 1556-5653
• DOI: 10.1016/S0015-0282(16)56773-9

Controlled ovarian hyperstimulation was given to a study group consisting of male factor, endometriosis, and unexplained infertility. The aim of the study was to determine whether COH might be of value for such couples in a setting lacking ART facilities. When compared with their own spontaneous cycles or with a control group (untreated but scanned), COH proved significantly better for unexplained infertility. However, COH was not significantly effective for male factor infertility. This study shows that COH should be offered routinely in general hospitals to couples on long-term waiting lists for ART (especially those facing enforced expectant management).