ENZYME-CATALYZED HYDROLYSIS OF THE DIBUTYLESTER OF (+/-) E,E-2,8-BISHYDROXYMETHYL-1,7-DIOXASPIRO[5,5]UNDECANE

The title compound was converted into the corresponding (2S,6S,8S) monoester with 94 % e.e. by porcine pancreatic lipase (PPL) in water/DMF (9/1).

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Bibliographic Details
Published inTetrahedron: asymmetry Vol. 2; no. 1; pp. 31 - 34
Main Authors GOURCY, JG, DAUPHIN, G, JEMINET, G
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 01.01.1991
Subjects
Chemistry
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Chemistry, Physical
Physical Sciences
Science & Technology
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Summary:The title compound was converted into the corresponding (2S,6S,8S) monoester with 94 % e.e. by porcine pancreatic lipase (PPL) in water/DMF (9/1).
ISSN:0957-4166
DOI:10.1016/S0957-4166(00)82152-7