Phase transfer of fatty acids into ultrasmall nanospheres for colorimetric detection of lipase and albumin
Colorimetric detection of fatty acids during biological interactions is extremely difficult since they are optically silent. Here, fatty acids are found to function as ion-exchangers in ultrasmall polymeric nanospheres to facilitate the protonation of chromoionophores, causing a vivid color change b...
Saved in:
Published in | Chemical communications (Cambridge, England) Vol. 58; no. 32; pp. 537 - 54 |
---|---|
Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
England
Royal Society of Chemistry
19.04.2022
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Colorimetric detection of fatty acids during biological interactions is extremely difficult since they are optically silent. Here, fatty acids are found to function as ion-exchangers in ultrasmall polymeric nanospheres to facilitate the protonation of chromoionophores, causing a vivid color change between red and blue. With an excellent detection limit of 1.8 μg mL
−1
for oleic acid, colorimetric assays for lipase and albumin are developed with quick response, high sensitivity, and low cost.
This work reports the colorimetric real-time monitoring of the reaction and transfer of fatty acids from natural triglycerides. |
---|---|
Bibliography: | 10.1039/d2cc01089e Electronic supplementary information (ESI) available. See DOI ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/d2cc01089e |