Cyclodextrin capped gold nanoparticles (AuNP@CDs): from synthesis to applications

As a multifunctional platform, cyclodextrin capped gold nanoparticles (AuNP@CDs) have attracted extensive attention due to their advantages of high specific surface area and high loading capacity. AuNP@CDs have a core-shell structure, retaining the advantages of the two materials. AuNPs act as the s...

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Published inJournal of materials chemistry. B, Materials for biology and medicine Vol. 9; no. 11; pp. 2584 - 2593
Main Authors Wang, Yichuan, Han, Yufen, Tan, Xiaoling, Dai, Yu, Xia, Fan, Zhang, Xiaojin
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 21.03.2021
Subjects
Catalysis
Core-shell structure
Cyclodextrin
Cyclodextrins
Drug delivery
Gold
Hydrophobicity
Medical imaging
Nanoparticles
Synthesis
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Summary:As a multifunctional platform, cyclodextrin capped gold nanoparticles (AuNP@CDs) have attracted extensive attention due to their advantages of high specific surface area and high loading capacity. AuNP@CDs have a core-shell structure, retaining the advantages of the two materials. AuNPs act as the support for the monolayer assembly of CDs. Some functional molecules can enter the hydrophobic cavity of CD through the host-guest interaction. In this brief review, we discuss the strategies for the synthesis of AuNP@CDs depending on the type and order of bonding. Their applications in drug delivery, catalysis, detection and bioimaging are highlighted. We hope to further stimulate AuNP@CD related research. The synthesis of AuNP@CDs is summarized according to the type and order of bonding. The applications of AuNP@CDs are also highlighted.
Bibliography:Dr Yu Dai is currently an associate professor at China University of Geosciences (Wuhan). She received her BSc degree (2007) and PhD degree (2012) from Wuhan University (Shengli Chen's group). She then joined China University of Geosciences (Wuhan) in 2012. She worked as a postdoctoral fellow in Prof. Kai Sun's group at the University of Michigan, Ann Arbor from June 2013 to August 2014. Her scientific interest is focused on chemical and biosensor field.
Dr Xiaojin Zhang is currently a professor at China University of Geosciences (Wuhan). He received his BSc degree (2007) and PhD degree (2012) from Wuhan University (Renxi Zhuo's group). He then worked as a postdoctoral fellow in Prof. Peter X. Ma's group at the University of Michigan, Ann Arbor. He joined China University of Geosciences (Wuhan) in 2016. His scientific interest is focused on biomedical polymers.
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ISSN:2050-750X
2050-7518
DOI:10.1039/d0tb02857f