Synthesis, reactions and application of chalcones: a systematic review

Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structureactivity relationships, and biological activities, is summarized herein. Along...

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Published inOrganic & biomolecular chemistry Vol. 21; no. 26; pp. 5317 - 5346
Main Authors Shalaby, Mona A, Rizk, Sameh A, Fahim, Asmaa M
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 05.07.2023
Subjects
Anti-Bacterial Agents - pharmacology
Anticancer properties
Antineoplastic Agents - pharmacology
Biological activity
Biological effects
Chalcone
Chalcones - pharmacology
Chemical synthesis
Inflammation
Pharmacology
Prospective Studies
R&D
Research & development
Structure-Activity Relationship
Toxicity
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Summary:Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structureactivity relationships, and biological activities, is summarized herein. Along with their toxicity and safety profiles, the prospective usage of chalcones in medicinal research and development is discussed. This review emphasizes the need for additional research in order to fully examine the therapeutic potential of chalcones as therapeutic agents for the treatment of a variety of disorders. Chalcones, Reactions, Synthesis, Biological activity, Industrial application.
Bibliography:ObjectType-Article-2
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ObjectType-Review-1
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ISSN:1477-0520
1477-0539
DOI:10.1039/d3ob00792h