A dual-site controlled pH probe revealing the pH of sperm cytoplasm and screening for healthy spermatozoa
A dual-site controlled pH probe, which is composed of gold nanoparticles and modified with rhodamine and fluorescein derivatives, was applied to sensitively monitor intracellular pH changes in sperm. The pH probe revealed the intracellular pH of sperm under different conditions and demonstrated the...
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Published in | Journal of materials chemistry. B, Materials for biology and medicine Vol. 9; no. 17; pp. 3662 - 3665 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Royal Society of Chemistry
05.05.2021
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Subjects | |
Online Access | Get full text |
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Summary: | A dual-site controlled pH probe, which is composed of gold nanoparticles and modified with rhodamine and fluorescein derivatives, was applied to sensitively monitor intracellular pH changes in sperm. The pH probe revealed the intracellular pH of sperm under different conditions and demonstrated the lower pH in asthenozoospermia patients as compared to healthy individuals. Importantly, the pH probe can help screen for healthy sperm.
A dual-site controlled pH probe was applied to sensitively monitor intracellular pH changes in spermatozoa. And it could observed the intracellular pH of sperm from asthenozoospermia patients was significantly lower than healthy individuals. |
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Bibliography: | 10.1039/d1tb00108f Electronic supplementary information (ESI) available. See DOI ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2050-750X 2050-7518 |
DOI: | 10.1039/d1tb00108f |