Modulating confinement space in metal-organic frameworks enables highly selective indole C3-formylation

• Published in: Chemical communications (Cambridge, England) Vol. 6; no. 44; pp. 5715 - 5718
• Main Authors: Zheng, Deng-Yue, Zhang, Tianjian, Bai, Rongxian, Li, Minghao, Gu, Yanlong
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 28.05.2024
• Subjects: Density functional theory; Metal-organic frameworks

Here, Selective C3-formylation of indole was achieved under mild conditions using a metal-organic framework (MOF) catalyst. The confined reaction space within the MOF pores effectively suppressed undesired side reactions and promoted the formation of the targeted product by controlling the reaction...