Palladium-catalyzed carbonylative bis(indolyl)methanes synthesis with TFBen as the CO source

[Display omitted] •The first example on carbonylative synthesis of bis(indolyl)methanes.•With TFBen (benzene-1,3,5-triyl triformate) as the solid CO source, no CO gas manipulation is needed.•Broad substrates scope, and giving the corresponding bis(indolyl)methane derivatives in moderate to excellent...

Full description

Saved in:
Bibliographic Details
Published inJournal of catalysis Vol. 362; pp. 74 - 77
Main Authors Qi, Xinxin, Ai, Han-Jun, Zhang, Ning, Peng, Jin-Bao, Ying, Jun, Wu, Xiao-Feng
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.06.2018
Subjects
Carbonylation
CO surrogate
Domino reaction
Indoles
Palladium catalyst
Carbonylation
Indoles
Palladium catalyst
CO surrogate
Domino reaction
Online AccessGet full text

Cover

More Information
Summary:[Display omitted] •The first example on carbonylative synthesis of bis(indolyl)methanes.•With TFBen (benzene-1,3,5-triyl triformate) as the solid CO source, no CO gas manipulation is needed.•Broad substrates scope, and giving the corresponding bis(indolyl)methane derivatives in moderate to excellent yields. An efficient and convenient palladium-catalyzed carbonylative procedure for the synthesis of bis(indolyl)methanes has been established for the first time. With TFBen (benzene-1,3,5-triyl triformate) as the solid CO source, aryl iodides and indoles were transformed into the corresponding bis(indolyl)methane derivatives in moderate to excellent yields.
ISSN:0021-9517
1090-2694
DOI:10.1016/j.jcat.2018.03.028