Optimization of the organic solvent-stable asymmetric hydrogen transfer system of Rhodococcus ruber DSM 44541: an activity-growth study

• Published in: Journal of molecular catalysis. B, Enzymatic Vol. 22; no. 1; pp. 1 - 6
• Main Authors: Kosjek, B., Stampfer, W., Glueck, S.M., Pogorevc, M., Ellmer, U., Wallner, S.R., Koegl, M.F., Poessl, T.M., Mayer, S.F., Ueberbacher, B., Faber, K., Kroutil, W.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.04.2003; Elsevier Science
• Subjects: Activity-growth; Bioconversions. Hemisynthesis; Biological and medical sciences; Biotechnology; Fermentation; Fundamental and applied biological sciences. Psychology; Methods. Procedures. Technologies; Rhodococcus ruber; sec-Alcohol dehydrogenase; Activity-growth; Rhodococcus ruber; Fermentation; sec-Alcohol dehydrogenase; Microorganism growth; Enzyme; Rhodococcus; Alcohol dehydrogenase; Optimization; Organic solvent; Enzymatic activity; Bacteria; Actinomycetes; Oxidoreductases

The organic solvent-stable redox-system of Rhodococcus ruber DSM 44541, which allows the efficient oxidation/reduction of sec-alcohols/ketones at the expense of acetone/2-propanol, respectively, as cosubstrate was optimized with respect to a maximum of alcohol dehydrogenase activity during cell grow...