Carbon dot enhanced peroxidase-like activity of platinum nanozymes
As one of the most intriguing nanozymes, the platinum (Pt) nanozyme has attracted tremendous research interest due to its various catalytic activities but its application is still limited by its poor colloidal stability and low affinity to substrates. Here, we design a highly stable Pt@carbon dot (P...
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Published in | Nanoscale Vol. 16; no. 9; pp. 4637 - 4646 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Royal Society of Chemistry
29.02.2024
|
Subjects | |
Online Access | Get full text |
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Summary: | As one of the most intriguing nanozymes, the platinum (Pt) nanozyme has attracted tremendous research interest due to its various catalytic activities but its application is still limited by its poor colloidal stability and low affinity to substrates. Here, we design a highly stable Pt@carbon dot (Pt@CD) hybrid nanozyme with enhanced peroxidase (POD)-like activity (specific activity of 1877 U mg
−1
). The Pt@CDs catalyze the decomposition of hydrogen peroxide (H
2
O
2
) to produce singlet oxygen and hydroxyl radicals and exhibit high affinity to H
2
O
2
and high specificity to 3,3′,5,5′-tetramethyl-benzidine. We reveal that both the hydroxyl and carbonyl groups of CDs could coordinate with Pt
2+
and then regulate the charge state of the Pt nanozyme, facilitating the formation of Pt@CDs and improving the POD-like activity of Pt@CDs. Colorimetric detection assays based on Pt@CDs for H
2
O
2
, dopamine, and glucose with a satisfactory detection performance are achieved. Moreover, the Pt@CDs show a H
2
O
2
-involving antibacterial effect by destroying the cell membrane. Our findings provide new opportunities for designing hybrid nanozymes with desirable stability and catalytic performance by using CDs as nucleating templates and stabilizers.
Carbon dots regulate the charge state of Pt nanozymes, enhancing the peroxidase-like activity of Pt@carbon and achieving colorimetric detection assays for hydrogen peroxide, dopamine, and glucose as well as the antibacterial effect. |
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Bibliography: | https://doi.org/10.1039/d3nr04964g Angew. Chem. Adv. Funct. Mater. Nano Today She has published >30 journal papers in Exploration Nat. Commun. and other leading journals with >2000 citations. , Electronic supplementary information (ESI) available. See DOI Dr Cui Liu obtained her Ph.D. in analytical chemistry at Wuhan University in 2017. She is currently an associate professor at Chongqing University. Her research focuses on the synthesis, functionalization, catalytic mechanism, and applications of carbon dot nanozymes. Dr Liu serves as an academic editor of ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2040-3364 2040-3372 |
DOI: | 10.1039/d3nr04964g |