Synthesis of 1,2,4-Trithiolanes from Thione S-Oxides and Lawesson Reagent at Room Temperature

The reaction of 2,2,4,4-tetramethyl-3-thioxocyclobutanone S-oxide with Lawesson reagent (L. R.) afforded the corresponding 1,2,4-trithiolane. Thiopivalophenone and thiopivalophenone S-oxides reacted with L. R. at rt to give the corresponding S-sulfide, which further reacted with thiones to afford th...

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Bibliographic Details
Published inBulletin of the Chemical Society of Japan Vol. 77; no. 1; pp. 187 - 188
Main Authors Okuma, Kentaro, Shigetomi, Toshiyuki, Shibata, Shinji, Shioji, Kosei
Format Journal Article
LanguageEnglish
Published TOKYO The Chemical Society of Japan 01.01.2004
Chemical Soc Japan
Chemical Society of Japan
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
DITHIIRANES
CHEMISTRY
SULFURIZATION
THIOKETONES
SULFIDES
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Summary:The reaction of 2,2,4,4-tetramethyl-3-thioxocyclobutanone S-oxide with Lawesson reagent (L. R.) afforded the corresponding 1,2,4-trithiolane. Thiopivalophenone and thiopivalophenone S-oxides reacted with L. R. at rt to give the corresponding S-sulfide, which further reacted with thiones to afford the corresponding cis-1,2,4-trithiolanes.
ISSN:0009-2673
1348-0634
DOI:10.1246/bcsj.77.187