Unusual Forms of Adrenal and Extra-Adrenal Myelolipomas

Myelolipomas are rare benign tumors of poorly understood tumorigenesis composed of mature hematopoietic tissue and fat. They mostly occur in the adrenal glands, but extra-adrenal myelolipomas have been reported in other locations such as the presacral region or retroperitoneum. It is not unusual tha...

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Published inInternational journal of surgical pathology Vol. 22; no. 5; p. 473
Main Authors Suárez-Peñaranda, José Manuel, Bermúdez Naveira, Anaberta, Fraga, Máximo, Aliste-Santos, Carlos, Cordeiro, Cristina, Muñoz-Barús, José Ignacio
Format Journal Article
LanguageEnglish
Published United States 01.08.2014
Subjects
Adrenal Gland Neoplasms - pathology
Aged
Female
Humans
Incidental Findings
Male
Middle Aged
Myelolipoma - pathology
Retroperitoneal Neoplasms - pathology
liver neoplasms
retroperitoneal tumors
combined neoplasms
myelolipomas
extra-adrenal myelolipomas
multiple neoplasms
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Summary:Myelolipomas are rare benign tumors of poorly understood tumorigenesis composed of mature hematopoietic tissue and fat. They mostly occur in the adrenal glands, but extra-adrenal myelolipomas have been reported in other locations such as the presacral region or retroperitoneum. It is not unusual that they are incidental findings revealed in the study of different diseases. We report 3 unusual examples of myelolipomas. The first is a multiple, unusually large, extra-adrenal myelolipoma, presented as an autopsy finding in an individual who had died suddenly from a central nervous system hemorrhage. The remaining 2 were incidental findings in patients studied for different reasons. Both were located within another neoplasm, namely an adrenal adenoma and a liver focal nodular hyperplasia. Moreover, the first showed infiltration by a non-Hodgkin lymphoma.
ISSN:1940-2465
DOI:10.1177/1066896914521289