Multi-effective nanoplatform with down/upconversion dual-mode emissions for NIR-II imaging and PDT/PTT synergistic therapy of early atherosclerosis

We design a multi-effective nanoplatform (CeO 2 :Nd@SiO 2 @CeO 2 :Yb,Er@SiO 2 -RB/MB/CD36) with down/upconversion dual-mode emissions and targeting ability in foam macrophages. Under NIR excitation, this nanoplatform can realize in vivo NIR-II imaging and PDT/PTT coordinated therapy for early AS sim...

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Published inChemical communications (Cambridge, England) Vol. 6; no. 75; pp. 1386 - 1389
Main Authors Gao, Wen, Lv, Lijun, Li, Guanghan, Zhao, Hongxiu, Zhou, Jia, Cheng, Yuan, Tang, Bo
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 16.09.2024
Subjects
Atherosclerosis
Cerium oxides
Erbium
Macrophages
Silicon dioxide
Upconversion
Ytterbium
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Summary:We design a multi-effective nanoplatform (CeO 2 :Nd@SiO 2 @CeO 2 :Yb,Er@SiO 2 -RB/MB/CD36) with down/upconversion dual-mode emissions and targeting ability in foam macrophages. Under NIR excitation, this nanoplatform can realize in vivo NIR-II imaging and PDT/PTT coordinated therapy for early AS simultaneously. We design a multi-effective nanoplatform with down/upconversion dual-mode emissions for NIR-II imaging and PDT/PTT synergistic therapy of early atherosclerosis.
Bibliography:Electronic supplementary information (ESI) available: Experimental procedures, material analysis and supporting figures. See DOI
https://doi.org/10.1039/d4cc03538k
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ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/d4cc03538k