Electroactive polymer tag modified nanosensors for enhanced intracellular ATP detection

• Published in: Analyst (London) Vol. 149; no. 13; pp. 353 - 3536
• Main Authors: Kang, Yi-Ran, Jiao, Yu-Ting, Zhao, Chen-Fei, Zhang, Xin-Wei, Huang, Wei-Hua
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 24.06.2024
• Subjects: Adenosine Triphosphate - analysis; Amplification; Aptamers, Nucleotide - chemistry; Biosensing Techniques - methods; Electroactive polymers; Electrochemical Techniques - instrumentation; Electrochemical Techniques - methods; Electrodes; Ferrous Compounds - chemistry; Gold - chemistry; HeLa Cells; Humans; Limit of Detection; Metallocenes - chemistry; Nanosensors; Nanowires; Nanowires - chemistry; Polymers; Polymers - chemistry

ATP plays a crucial role in cell energy supply, so the quantification of intracellular ATP levels is particularly important for understanding many physio-pathological processes. The intracellular quantification of this non-electroactive molecule can be realized using aptamer-modified nanoelectrodes,...