Synthesis, characterization and biological evaluation of poly [LA-co-(Glc-alt-Lys)] for nerve regeneration scaffold

• Published in: Frontiers of materials science Vol. 8; no. 1; pp. 95 - 101
• Main Authors: YIN, Yi-Xia, YI, Ji-Ling, XIE, Li-Juan, YAN, Qiong-Jiao, DAI, Hong-Lian, LI, Shi-Pu
• Format: Journal Article
• Language: English
• Published: Heidelberg Higher Education Press 01.03.2014
• Subjects: biocompatibility; Chemistry and Materials Science; implantation; inflammatory factor; Materials Science; poly [LA-co-(Glc-alt-Lys)] (PLGL); Research Article; Schwann cell (SC); implantation; inflammatory factor; Schwann cell (SC); biocompatibility; poly [LA-co-(Glc-alt-Lys)] (PLGL)

A novel nerve repairing material poly [LA-co-(Glc-alt-Lys)] (PLGL) was synthesized. The viability and growth of Schwann cells (SCs) co-cultured with poly (D, L-lactic acid) (PDLLA) films (control group) and PLGL films were evaluated by MTT assay and SEM observation. Then, contact angle measurement,...