Synthetic approaches to regiospecifically mono- and dilabelled arenes

• Published in: Journal of labelled compounds & radiopharmaceuticals Vol. 54; no. 1; pp. 1 - 32
• Main Authors: Gregson, Thomas J., Herbert, John M., Row, Eleanor C.
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.01.2011; Wiley
• Subjects: arene synthesis; aromatic substitution; Chemistry; Exact sciences and technology; Labelled compounds chemistry; monolabelled arenes; Organic chemistry; Reactivity and mechanisms; Radiolabelling; Carbon Isotopes; Review; Radioisotope; Regiospecificity; arene synthesis; Carbon 11; Aromatic compound; Aromatic substitution; Chemical synthesis; monolabelled arenes; Carbon 14; Carbon 13; Labelled compound
• ISSN: 0362-4803; 1099-1344
• DOI: 10.1002/jlcr.1783

A variety of methods for the preparation of selectively mono‐, di‐ or tri‐labelled arenes are reviewed. The review concentrates on those for which the application to labelled synthesis has been demonstrated. Further methods, the application of which to labelled synthesis appears viable but which have not been reduced to practise, are included also. The available methods provide a range of substitution patterns. Copyright © 2010 John Wiley & Sons, Ltd. A variety of methods for the preparation of selectively mono‐, di‐ or trilabelled arenes are reviewed. The review concentrates on those for which the application to labelled synthesis has been demonstrated. Further methods, the application of which to labelled synthesis appears viable but which have not been reduced to practice, are also included. The available methods provide a range of substitution patterns. Copyright © 2010 John Wiley & Sons, Ltd.