Ageing and problems in differential diagnosis of psychoorganic syndromes

Depressive syndrome was investigated in 132 psychiatric and neurologic patients by Zung's self-rating depression scale. The dexamethasone suppression test (DST) was carried out in 62 patients. Visual evoked potentials (VEP) (stimulation with flash (F-VEP) and pattern (P-VEP)), serum levels of L...

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Published inArchives of gerontology and geriatrics Vol. 16; no. 2; pp. 177 - 189
Main Authors Molnár, G., Glaub, T., Such, Á., Bazsáné, K.Zs, Pék, Gy, Csiky-Mészáros, M., Fülöp, T.
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 01.03.1993
Elsevier
Subjects
Biological and medical sciences
Dementia
Depression
Geriatrics
Hormones
Medical sciences
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Visual evoked potentials
Depression
Visual evoked potentials
Hormones
Dementia
Human
Mood disorder
Nervous system diseases
Cognitive disorder
Psychoorganic syndrome
Electrophysiology
Visual evoked potential
Electroencephalography
Differential diagnostic
Cerebral disorder
Senile dementia
Intellectual deterioration
Dexamethasone test
Mental disorder
Degenerative disease
Hormonal investigation
Elderly
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Summary:Depressive syndrome was investigated in 132 psychiatric and neurologic patients by Zung's self-rating depression scale. The dexamethasone suppression test (DST) was carried out in 62 patients. Visual evoked potentials (VEP) (stimulation with flash (F-VEP) and pattern (P-VEP)), serum levels of LH, FSH, prolactin, ACTH, estradiol and cortisol were measured in 15 female patients between 85 and 94 years of age. Abnormal DST results indicated depression rather than dementia. P-VEP latencies correlated with cognitive symptoms, while F-VEP latencies correlated with affective symptoms. Gonadotropin levels were lowered in senility in comparison with the climacteric period of life. Depressive, anxious, cognitive, anorexic, sexual and disturbed diurnal mood changes syndromes could be separated by factor analysis. The severity of the cognitive depressive syndrome correlated negatively with estradiol serum levels. The total scores of Zung's self-rating depression scales correlated positively with ACTH and negatively with FSH serum levels.
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ISSN:0167-4943
1872-6976
DOI:10.1016/0167-4943(93)90008-6