A NEW PEPTIDE-BOND SURROGATE - 2-ISOXAZOLINE IN PSEUDODIPEPTIDE CHEMISTRY

The 2-isoxazoline ring has been incorporated as a new peptide bond surrogate into pseudodipeptide. An easy and versatile general method for the preparation of pseudodipeptides is described.

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Bibliographic Details
Published inTetrahedron letters Vol. 33; no. 45; pp. 6811 - 6814
Main Authors KIM, BH, CHUNG, YJ, KEUM, GC, KIM, JH, KIM, KM
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 03.11.1992
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
DIPEPTIDE ISOSTERES
ALPHA-AMINO ALDEHYDES
DERIVATIVES
ASYMMETRIC INDUCTION
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Summary:The 2-isoxazoline ring has been incorporated as a new peptide bond surrogate into pseudodipeptide. An easy and versatile general method for the preparation of pseudodipeptides is described.
ISSN:0040-4039
DOI:10.1016/S0040-4039(00)61782-3