Kinetic determination of pKa in 2′-hydroxychalcones
A kinetic model that enables the determination of pKa of 2′(OH)-chalcone in 60% (w/w) ethanol-water, 32°C, pH 9–10 and ionic strength 0.001 is developed. Experimental data are obtained by UV/VIS and HPLC techniques. C:2′-Hydroxychalcone; F: Flavanone; E: Enol; Ka C, K R and K EF: Acid Dissociation,...
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Published in | Tetrahedron letters Vol. 34; no. 29; pp. 4615 - 4618 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Elsevier Ltd
03.09.1993
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | A kinetic model that enables the determination of pKa of 2′(OH)-chalcone in 60% (w/w) ethanol-water, 32°C, pH 9–10 and ionic strength 0.001 is developed. Experimental data are obtained by UV/VIS and HPLC techniques.
C:2′-Hydroxychalcone; F: Flavanone; E: Enol; Ka
C, K
R and K
EF: Acid Dissociation, Partition and Enolization Constants; cy: cyclohexane; ol-w: ethanol-water 60% w/w |
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ISSN: | 0040-4039 1873-3581 |
DOI: | 10.1016/S0040-4039(00)60638-X |