Genetic risk factors for autoimmune diseases

In most autoimmune diseases multigenic factors play a significant role in pathogenesis. Progress in identifying these genetic factors, many of which are located outside the major histocompatibility complex, was the subject of a recent meeting.

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Bibliographic Details
Published inImmunology today Vol. 20; no. 1; pp. 10 - 12
Main Authors Feltkamp, T E, Aarden, L A, Lucas, C J, Verweij, C L, de Vries, R R
Format Journal Article Conference Proceeding
LanguageEnglish
Published England 01.01.1999
Subjects
Animals
Apoptosis
Arthritis, Experimental - genetics
Arthritis, Experimental - immunology
Arthritis, Rheumatoid - genetics
Arthritis, Rheumatoid - immunology
Autoimmune Diseases - genetics
Autoimmune Diseases - immunology
Celiac Disease - genetics
Celiac Disease - immunology
Diabetes Mellitus, Type 1 - genetics
Diabetes Mellitus, Type 1 - immunology
Genetic Predisposition to Disease
Humans
Interleukin-10 - genetics
Interleukin-10 - physiology
Mice
Mice, Inbred MRL lpr
Mice, Knockout
Multiple Sclerosis - genetics
Multiple Sclerosis - immunology
Risk Factors
Transforming Growth Factor beta - genetics
Transforming Growth Factor beta - physiology
Tumor Necrosis Factor-alpha - genetics
Tumor Necrosis Factor-alpha - physiology
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Summary:In most autoimmune diseases multigenic factors play a significant role in pathogenesis. Progress in identifying these genetic factors, many of which are located outside the major histocompatibility complex, was the subject of a recent meeting.
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ISSN:0167-5699
DOI:10.1016/S0167-5699(98)01347-4