Fabrication and electrochemical study of carbon modified TiO2 nanowires

We report on the direct growth of TiO2 nanowires via a facile thermal oxidation treatment of a Ti substrate, and their capacity for electrochemical biosensing. To improve the conductivity of the TiO2 nanowires and to facilitate the immobilization of enzymes onto their surfaces, a thin layer of carbo...

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Bibliographic Details
Published inElectrochemistry communications Vol. 49; pp. 25 - 29
Main Authors Ahmadalinezhad, Asieh, Wu, Guosheng, Keeler, Werden, Chen, Aicheng
Format Journal Article
LanguageEnglish
Published Lausanne Elsevier B.V 01.12.2014
Amsterdam Elsevier
New York, NY
Subjects
Biological and medical sciences
Biosensor
Biosensors
Biotechnology
Direct electrochemistry
Fundamental and applied biological sciences. Psychology
Glucose oxidase
Methods. Procedures. Technologies
TiO2 nanowires
Various methods and equipments
Glucose oxidase
TiO2 nanowires
Direct electrochemistry
Biosensor
Human
Phosphates
Titanium IV Oxides
Biological fluid
Aldose
Enzyme
Immobilization
Glucose
Buffer solution
Carbon
Chemical vapor deposition
Blood
Electrochemistry
Oxidoreductases
Nanowires
TiO
Chronoamperometry
Blood serum
Modified material
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Summary:We report on the direct growth of TiO2 nanowires via a facile thermal oxidation treatment of a Ti substrate, and their capacity for electrochemical biosensing. To improve the conductivity of the TiO2 nanowires and to facilitate the immobilization of enzymes onto their surfaces, a thin layer of carbon was deposited on the surface of TiO2 nanowires via chemical vapor deposition. Upon the immobilization of glucose oxidase as a model protein, direct electron transfer was observed in a mediator-free biosensing environment. Our electrochemical studies have revealed that the designed glucose biosensor exhibits a wide linear range of up to 18mM glucose, along with high sensitivity and selectivity. The developed biosensor was further tested using human serum samples and has demonstrated promising results for medical applications. •Direct growth of TiO2 nanowires for electrochemical biosensing•Modification of TiO2 nanowires with a thin carbon layer•Upon the immobilization of glucose oxidase, direct electron transfer was observed.•Glucose biosensor with a wide linear range, high sensitivity and selectivity
ISSN:1388-2481
1873-1902
DOI:10.1016/j.elecom.2014.10.001