Synthesis and Biological Activity of Some 3,4‐Dihydro‐4‐(4‐substituted aryl)‐6‐(naptho[2,1‐b]furan‐2‐yl pyrimidine‐2(1H)‐one Derivatives

A series of new oxopyrimidine were prepared by cyclocondensation route with various substituted chalcones in presence of alcoholic solution of potassium hydroxide at reflux temperature. The synthesized oxopyrimidine derivatives were characterized by means of their IR, 1 H NMR, mass spectral data and...

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Published inE-journal of chemistry Vol. 9; no. 1; pp. 175 - 180
Main Authors Gaikwad, Sanjeevan S., Suryawanshi, Venkat S., Lohar, Kishan S., Jadhav, Dhanaji V., Shinde, Narayan D.
Format Journal Article
LanguageEnglish
Published Wiley 01.01.2012
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Summary:A series of new oxopyrimidine were prepared by cyclocondensation route with various substituted chalcones in presence of alcoholic solution of potassium hydroxide at reflux temperature. The synthesized oxopyrimidine derivatives were characterized by means of their IR, 1 H NMR, mass spectral data and elemental analysis. The synthesized oxopyrimidines derivatives were evaluated for antibacterial and antifungal activities, some of them were found to possess significant activity.
ISSN:2090-9063
0973-4945
2090-9071
2090-9810
DOI:10.1155/2012/258672