Comment on "Cortical folding scales universally with surface area and thickness, not number of neurons"

Mota and Herculano-Houzel (Reports, 3 July 2015, p. 74) assign power functions to neuroanatomical data and present a model to account for evolutionary patterns of cortical folding in the mammalian brain. We detail how the model assumptions are in conflict with experimental and observational work and...

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Published inScience (American Association for the Advancement of Science) Vol. 351; no. 6275; p. 825
Main Authors Lewitus, Eric, Kelava, Iva, Kalinka, Alex T, Tomancak, Pavel, Huttner, Wieland B
Format Journal Article
LanguageEnglish
Published United States The American Association for the Advancement of Science 19.02.2016
Subjects
Animals
Cerebral Cortex
Humans
Lissencephaly - pathology
Neurons - cytology
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Summary:Mota and Herculano-Houzel (Reports, 3 July 2015, p. 74) assign power functions to neuroanatomical data and present a model to account for evolutionary patterns of cortical folding in the mammalian brain. We detail how the model assumptions are in conflict with experimental and observational work and show that the model itself does not accurately fit the data.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ObjectType-Commentary-3
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ISSN:0036-8075
1095-9203
DOI:10.1126/science.aad2029