An expedient approach to enhance Mizoroki-Heck coupling reaction by infrared irradiation using palladacycle compounds

• Published in: Applied organometallic chemistry Vol. 29; no. 8; pp. 556 - 560
• Main Authors: Ortega-Jiménez, Fernando, Domínguez-Villa, Francisco X., Rosas-Sánchez, Alfredo, Penieres-Carrillo, Guillermo, López-Cortés, José G., Ortega-Alfaro, M. Carmen
• Format: Journal Article
• Language: English
• Published: Blackwell Publishing Ltd 01.08.2015
• Subjects: Catalytic activity; Infrared; infrared irradiation; Irradiation; Joining; Metalorganic compounds; Microwaves; Mizoroki-Heck reaction; palladacycles; Reaction time; Strategy
• ISSN: 0268-2605; 1099-0739
• DOI: 10.1002/aoc.3331

An alternative and environmentally friendly strategy to promote the Mizoroki–Heck cross‐coupling reaction by the use of infrared irradiation using palladacycles as precatalysts is reported. Coupling products are obtained in high yield and short reaction time. A comparison with the classical use of reflux conditions, and commercial sources of palladium complexes, shows the advantages of this new alternative for promoting coupling reactions. Copyright © 2015 John Wiley & Sons, Ltd. The catalytic activity of three palladacycles (2, 3a and 3b) as precatalysts in the Mizoroki–Heck reaction is reported. The use of infrared irradiation to enhance this coupling reaction in comparison with microwaves shows comparable advantages of this new synthetic alternative.