Endocrinologic evaluation of impotence

Among 600 impotent men who had endocrine evaluation for androgen deficiency, thyroid deficiency, and hyperprolactinemia, 192 (32%) were found to have an endocrine abnormality. Androgen deficiency was divided into primary testicular failure and "hypothalamic-pituitary dysfunction" by an and...

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Bibliographic Details
Published inSouthern medical journal (Birmingham, Ala.) Vol. 82; no. 4; p. 446
Main Author Baskin, H J
Format Journal Article
LanguageEnglish
Published United States 01.04.1989
Subjects
Erectile Dysfunction - blood
Erectile Dysfunction - complications
Follicle Stimulating Hormone - blood
Follow-Up Studies
Gonadotropins, Pituitary - blood
Humans
Hypothalamo-Hypophyseal System - metabolism
Hypothyroidism - blood
Hypothyroidism - complications
Luteinizing Hormone - blood
Male
Middle Aged
Prolactin - blood
Testosterone - blood
Thyrotropin - blood
Thyroxine - blood
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Summary:Among 600 impotent men who had endocrine evaluation for androgen deficiency, thyroid deficiency, and hyperprolactinemia, 192 (32%) were found to have an endocrine abnormality. Androgen deficiency was divided into primary testicular failure and "hypothalamic-pituitary dysfunction" by an androgen quotient derived using simultaneous gonadotropin and testosterone levels. This androgen quotient was found to correlate well with the response to testosterone and was more useful than the testosterone level in predicting which patients would benefit from long-term testosterone replacement. Unsuspected hypothyroidism (6%) and hyperprolactinemia (3%) were both common in this group of patients, and appropriate treatment reversed the impotence.
ISSN:0038-4348
DOI:10.1097/00007611-198904000-00010