Development and Validation of a New Dry Weight Estimation Method Using Single Frequency Bioimpedance in Hemodialysis Patients

Background: We proposed a new method to estimate dry weight (DW) using single frequency bioimpedance. Methods: We hypothesized that the change in whole body resistance at 50 kHz (R 50 ) was proportional to the ultrafiltration volume (UFV) during a hemodialysis (HD) session. When the targeted resista...

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Bibliographic Details
Published inBlood purification Vol. 32; no. 4; pp. 278 - 285
Main Authors Dou, Yanna, Cheng, Xuyang, Liu, Li, Bai, Xiafeng, Wu, Leiyun, Guo, Weiya, Zhao, Xinju, Wang, Fang, Cao, Liyun, Zuo, Li
Format Journal Article
LanguageEnglish
Published Basel, Switzerland Karger 01.01.2011
Subjects
Adolescent
Adult
Aged
Aged, 80 and over
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Body Composition
Body Weight
Electric Impedance
Emergency and intensive care: renal failure. Dialysis management
Female
Humans
Intensive care medicine
Linear Models
Male
Medical sciences
Middle Aged
Original Paper
Renal Dialysis - methods
Reproducibility of Results
Young Adult
Hemodialysis
Bioimpedance
Dry weight
Single frequency
Human
Estimation
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Summary:Background: We proposed a new method to estimate dry weight (DW) using single frequency bioimpedance. Methods: We hypothesized that the change in whole body resistance at 50 kHz (R 50 ) was proportional to the ultrafiltration volume (UFV) during a hemodialysis (HD) session. When the targeted resistance estimated in healthy subjects was reached, the patient achieved his/her DW. UFV and R 50 were monitored in 40 HD patients. Another 43 HD patients were stratified into 2 groups to validate this method. Results: The change in whole body resistance was proportional to UFV in each of the 40 HD patients. In the DW decrease group, pre-dialysis systolic blood pressure (n = 29, 154.5 ± 22.8 vs. 146.9 ± 22.3, p < 0.05) and antihypertensive medicine (4.7 ± 3.6 vs. 3.3 ± 2.2, p < 0.05) decreased without adverse symptoms change. In the DW increase group, the number of adverse symptoms in 1 week (n = 14, 26 vs. 6, p < 0.05) decreased without a change in systolic blood pressure. Conclusion: This method may become a convenient and cheaper way to estimate DW in HD patients.
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ISSN:0253-5068
1421-9735
DOI:10.1159/000330337