Neuroinflammation: An astrocyte perspective

Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles in health and disease. Recent technologies have uncovered the functional heterogeneity of astrocytes and their extensive interactions with other cell types in the CNS. In this Review, we highlight the intr...

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Published inScience translational medicine Vol. 15; no. 721; p. eadi7828
Main Authors Lee, Hong-Gyun, Lee, Joon-Hyuk, Flausino, Lucas E, Quintana, Francisco J
Format Journal Article
LanguageEnglish
Published United States 08.11.2023
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Abstract Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles in health and disease. Recent technologies have uncovered the functional heterogeneity of astrocytes and their extensive interactions with other cell types in the CNS. In this Review, we highlight the intricate interactions between astrocytes, other CNS-resident cells, and CNS-infiltrating cells as well as their potential therapeutic value in the context of inflammation and neurodegeneration.
AbstractList Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles in health and disease. Recent technologies have uncovered the functional heterogeneity of astrocytes and their extensive interactions with other cell types in the CNS. In this Review, we highlight the intricate interactions between astrocytes, other CNS-resident cells, and CNS-infiltrating cells as well as their potential therapeutic value in the context of inflammation and neurodegeneration.
Author Flausino, Lucas E
Lee, Hong-Gyun
Lee, Joon-Hyuk
Quintana, Francisco J
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Snippet Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles in health and disease. Recent technologies have uncovered the...
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SubjectTerms Astrocytes - metabolism
Central Nervous System
Humans
Inflammation - metabolism
Neuroglia
Neuroinflammatory Diseases
Title Neuroinflammation: An astrocyte perspective
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Volume 15
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