Degradation of Cylindrical Poly-Lactic Co-Glycolide/Beta-Tricalcium Phosphate Biocomposite Anchors After Arthroscopic Bankart Repair: A Prospective Study

• Published in: Orthopedics (Thorofare, N.J.) Vol. 41; no. 3; pp. e348 - 353
• Main Authors: Matsuki, Keisuke, Sugaya, Hiroyuki, Takahashi, Norimasa, Kawasaki, Takayuki, Yoshimura, Hideya, Kenmoku, Tomonori
• Format: Journal Article
• Language: English
• Published: United States SLACK INCORPORATED 01.05.2018
• Subjects: Acids; Arthritis; Biodegradable materials; Clinical trials; Knee; Patients; Shoulder; Studies; Surgery; Japan
• ISSN: 0147-7447; 1938-2367
• DOI: 10.3928/01477447-20180226-08

The purpose of this study was to examine widening and ossification of anchor holes after arthroscopic Bankart repair with the use of cylindrical biocomposite anchors made of 70% poly-L-lactide-co-glycolide acid (PLGA) and 30% beta-tricalcium phosphate (ß-TCP). Twenty-two patients were enrolled in a clinical trial to acquire marketing approval of a PLGA/ß-TCP biocomposite suture anchor in Japan and underwent arthroscopic Bankart repairs with the anchors. Eleven of 22 patients had computed tomography scans after 2-year follow-up. Three surgeons independently evaluated width and ossification of anchor holes in 4 grades using computed tomography scans. When the evaluations disagreed, the final grade was determined based on the 3 surgeons' consensus. Seven men and 4 women were evaluated at a mean of 30 months (range, 28-32 months) after surgery, and a total of 47 anchors were implanted. Anchor holes were narrowed in 39 (83%) of 47 anchor sites and were almost or completely filled in (type 3 or 4) in 21 (45%) of 47 anchor sites. Ossification was seen in 46 (98%) of 47 anchor sites and was nearly complete or complete (type 3 or 4) in 16 (34%) of 47 anchor sites. There were no significant differences in both anchor hole width and ossification score on comparison of the anteroinferior (4- to 6-o'clock positions in the right shoulder) with other anchor sites. Cylindrical biocomposite anchors made of 70% PLGA/30% ß-TCP showed a low incidence of anchor hole widening and excellent ossification regardless of anchor site. [Orthopedics. 2018; 41(3):e348-e353.].