Refractory anemia in systemic sclerosis: myelodisplastic syndrome

Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by small vessel vasculopathy, autoantibodies, and skin or visceral organ fibrosis (lung, oesophagus, kidney etc.) as a result of extracellular collagen deposition. The cancer risk is higher in many rheumatic diseases,...

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Bibliographic Details
Published inEuropean journal of rheumatology Vol. 2; no. 3; pp. 120 - 121
Main Authors Sargin, Gokhan, Senturk, Taskin, Yavasoglu, Irfan
Format Journal Article
LanguageEnglish
Published Turkey Medical Research and Education Association 01.09.2015
Subjects
Case Report
malignancy
myelodisplastic syndrome
Systemic sclerosis
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Summary:Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by small vessel vasculopathy, autoantibodies, and skin or visceral organ fibrosis (lung, oesophagus, kidney etc.) as a result of extracellular collagen deposition. The cancer risk is higher in many rheumatic diseases, including SSc. Various defined malignancies may develop in 3%-11% of patients with SSc. These solid tumors are generally observed in the lung, oesophagus, or breast. In addition, an increased risk for hematological cancers were reported in literature. Herein, we describe an interesting case of SSc complicated by myelodisplastic syndrome (MDS). Our aim is to draw attention to developing cancers and the rare occurence of MDS in patients with SSc.
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ISSN:2147-9720
2148-4279
DOI:10.5152/eurjrheum.2015.0100